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FplA From <i>Fusobacterium nucleatum</i> is a Type Vd autotransporter phospholipase with a proposed role in altered host signaling and evasion of autophagy

2017-05-10

Abstract excerpt

<h4>ABSTRACT</h4> Fusobacterium nucleatum is a pathogenic oral bacterium that is linked to multiple human infections and colorectal cancer. While most Gram-negative pathogens utilize secretion systems for cellular invasion and infection, F. nucleatum lacks Type I, II, III, IV, and VI secretion. By contrast, F. nucleatum strains are enriched in Type V secreted autotransporters, which are Gram-negative bacterial...

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Literature Corpus work
68af155f-c8eb-5e8a-92f2-7294e86503cc
DOI
10.1101/136598
Open publication

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