Article

PalmaClust: A graph-fusion framework leveraging the Palma ratio for robust ultra-rare cell type detection in scRNA-seq data

2026-03-18

Abstract excerpt

<h4>Motivation</h4> Single-cell RNA sequencing (scRNA-seq) is routinely used to build atlases of tissues, resolve developmental trajectories, and characterize disease microenvironments. Yet many biologically and clinically meaningful populations—including transient progenitors, therapy-resistant tumor subclones, and antigen-specific lymphocytes—occur at very low frequencies ( < 1%) and are easily missed by stand...

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Literature Corpus work: 687b3af9-3f57-5e56-af46-2de73cfe03d8
DOI: 10.64898/2026.03.16.712161

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