Article

Eukarion-134 attenuates endoplasmic reticulum stress-induced mitochondrial dysfunction in human skeletal muscle cells

2020-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Maladaptive endoplasmic reticulum (ER) stress is associated with modified reactive oxygen species (ROS) generation, altered mitochondrial bioenergetics, and oxidative damage; and is postulated as a potential mechanism involved in the underlying muscle weakness experienced by patients with myositis, an acquired autoimmune neuromuscular disease. In this study, we investigate the impact of ROS gene...

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Literature Corpus work: 686df5a3-b119-5f24-ab92-05d5d0f47c3d
DOI: 10.1101/2020.06.10.143958

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