Article

Exploring the impact of inoculum dose on host immunity and morbidity to inform model-based vaccine design

2018-05-22

Abstract excerpt

<h4>Background</h4> Vaccination is an effective method to protect against infectious diseases. An important consideration in any vaccine formulation is the inoculum dose, i.e., amount of antigen or live attenuated pathogen that is used. Higher levels generally lead to better stimulation of the immune response but might cause more severe side effects and allow for less population coverage in the presence of vaccin...

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Literature Corpus work: 686c7d54-dfc6-59b6-a83b-c905df0b6574
DOI: 10.1101/328559

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