Article

Dicer-independent miR-451a is Upregulated in Periodontitis and Potentiates Inflammation by Impairing Macrophage Polarization and SOCS Activity

2026-05-05

Abstract excerpt

<title>Abstract</title> <p>Periodontitis is characterized by localized inflammatory tissue destruction, yet the lesion-specific microRNA networks that shape host immune responses remain incompletely defined. Using a split-mouth design, we profiled miRNA expression in gingival biopsies obtained from periodontal lesions and clinically healthy sites within the same individuals to identify disease-associated regulato...

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Literature Corpus work: 68172911-6d82-5c8e-a62f-4da389647f28
DOI: 10.21203/rs.3.rs-9361339/v1

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