Article

Blunted Fas signaling favors RIPK1-driven neutrophil necroptosis in critically ill COVID-19 patients

2021-03-19

Abstract excerpt

Critically ill COVID-19 patients are characterized by a severely dysregulated cytokine profile and elevated neutrophil counts, which are thought to contribute to disease severity. However, to date it remains unclear how neutrophils contribute to pathophysiology during COVID-19. Here, we assessed the impact of the dysregulated cytokine profile on the tightly regulated cell death program of neutrophils. We show that...

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Literature Corpus work: 67bc7c7a-97e3-5659-a372-f590718616e3
DOI: 10.1101/2021.03.19.436166

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Blunted Fas signaling favors RIPK1-driven neutrophil necroptosis in critically ill COVID-19 patientsDOI 10.1101/2021.03.19.436166Read

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