Article
Dysregulated Neutrophil Phenotype and Function in Hospitalised Non-ICU COVID-19 Pneumonia.
Cells - 16 Sept 2022
Belchamber Kylie B R, Thein Onn S, Hazeldine Jon, Grudzinska Frances S, Faniyi Aduragbemi A, Hughes Michael J, Jasper Alice E, Yip Kay Por, Crowley Louise E, Lugg Sebastian T, Sapey Elizabeth, Parekh Dhruv, Thickett David R, Scott Aaron
Abstract excerpt
Rationale: Infection with the SARS-CoV2 virus is associated with elevated neutrophil counts. Evidence of neutrophil dysfunction in COVID-19 is based on transcriptomics or single functional assays. Cell functions are interwoven pathways, and understanding the effect across the spectrum of neutrophil function may identify therapeutic targets. Objectives: Examine neutrophil phenotype and function in 41 hospitalised,...
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