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Article

Caspase‐8: not so silently deadly

1 Jan 2017

Abstract excerpt

Apoptosis is a caspase-dependent programmed form of cell death, which is commonly believed to be an immunologically silent process, required for mammalian development and maintenance of cellular homoeostasis. In contrast, lytic forms of cell death, such as RIPK3- and MLKL-driven necroptosis, and caspase-1/11-dependent pyroptosis, are postulated to be inflammatory via the release of damage associated molecular...

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PMID: 28197335
DOI: 10.1038/cti.2016.83

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