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Evaluating <i>ANO6</i> as a Parkinson’s disease candidate gene: a human genetic investigation of common and rare variant associations

2026-01-23

Abstract excerpt

<h4>ABSTRACT</h4> ANO6 (TMEM16F) , a Ca 2 □-activated lipid scramblase and ion channel, has been implicated in α-synuclein secretion and propagation, a hallmark of Parkinson’s disease (PD). To evaluate whether genetic variation in ANO6 contributes to PD risk, we analyzed common and rare variants across large-scale datasets. Relying on genome-wide association study (GWAS) summary statistics from 63,555 PD cases,...

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Literature Corpus work
67883402-538e-56c1-b492-257e48e689e8
DOI
10.64898/2026.01.21.26344547
Open publication

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Evaluating <i>ANO6</i> as a Parkinson’s disease candidate gene: a human genetic investigation of common and rare variant associationsDOI 10.64898/2026.01.21.26344547
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