Article

A major Role for Nrf2 transcription factors in cell transformation by KSHV encoded oncogenes

2019-06-21

Abstract excerpt

<h4>ABSTRACT</h4> Kaposi‘s sarcoma (KS) is the most common tumor in AIDS patients and the highly vascularized patient‘s skin lesions are composed of the cells that derive from the endothelial tissue transformed by the KSHV virus. Heme oxygenase-1 (HO-1) is an enzyme upregulated by the Kaposi‘s sarcoma-associated herpesvirus (KSHV) and highly expressed in human Kaposi Sarcoma (KS) lesions. The oncogenic G protein-...

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Literature Corpus work: 674f7ea7-1bbf-5c01-9b74-ea8c1ebf9b43
DOI: 10.1101/678342

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