Article
The KSHV and other human herpesviral G protein-coupled receptors.
Current topics in microbiology and immunology - 1 Jan 2007
Cannon M
Abstract excerpt
Kaposi sarcoma-associated herpesvirus (KSHV) is a gamma2-herpesvirus discovered in 1994 and is the agent responsible for Kaposi sarcoma (KS), an endothelial cell malignancy responsible for significant morbidity and mortality worldwide. Over time, KSHV has pirated many human genes whose products regulate angiogenesis, inflammation, and the cell cycle. One of these encodes for a mutated G protein-coupled receptor...
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