Article

Fatigue-associated DNA methylation and gene expression profiles differ by disease subtype and activity state in inflammatory bowel disease patients

2026-06-08

Abstract excerpt

<h4>Background and Aims</h4> Fatigue is a prevalent and disabling symptom in inflammatory bowel disease (IBD), yet its underlying biological mechanisms remain poorly understood. We aimed to characterize fatigue-associated molecular signatures in IBD patients by integrating DNA methylation and mRNA expression analyses. <h4>Methods</h4> Peripheral blood was collected from 40 patients with Crohn’s disease (CD), 29...

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Literature Corpus work: 673318de-6a85-5a4f-b66a-15ec0ff23b70
DOI: 10.64898/2026.06.05.26354816

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