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Article

The Use of Quinacrine in Nitroimidazole-resistant Giardia Duodenalis: An Old Drug for an Emerging Problem.

The Journal of infectious diseases - 15 Mar 2017

Requena-Méndez Ana, Goñi Pilar, Rubio Encarnación, Pou Diana, Fumadó Victoria, Lóbez Silvia, Aldasoro Edelweiss, Cabezos Juan, Valls Maria Eugenia, Treviño Begoña, Martínez Montseny Antonio Federico, Clavel Antonio, Gascon Joaquim, Muñoz José

Abstract excerpt

Background: There is little evidence regarding the management of refractory giardiasis after treatment with nitroimidazoles. This study estimates the proportion of persistent giardiasis in 3 hospitals in Barcelona, describes associated risk factors and genotype, and evaluates the efficacy rate of quinacrine in those with persistent giardiasis. Methods: A clinical, prospective, observational study was conducted in...

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PMID: 28453841
DOI: 10.1093/infdis/jix066

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