Article

Identification of a kappaB-like motif at the 5^-upstream region of human lymphotoxin gene

1994-01-01

Abstract excerpt

Lymphotoxin(LT) is a glycoprotein secreted by activated T cell. The expression of LT gene is mainly regulated at the level of transcription. By using human LT DNA as a probe, we carried out a RNA dot blotting test and found that the longer the time of Jurkat human Tlymphoma cells exposed to the PMA and PHA, the more endogenous LT mRNA could be produced. Results of gel retardation assay showed that the nuclear extr...

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Identifiers and source

Literature Corpus work: 66bc9f1a-5886-5585-975c-55de73a5069e
DOI: 10.1038/cr.1994.1

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