Article

The Growth Hormone-IGF-1 axis is a risk factor for Long-Term Kidney Allograft Failure

2024-11-29

Abstract excerpt

<h4>Introduction</h4> Maladaptive hypertrophy and podocyte stress and depletion contribute to kidney function decline. Although IGF-1 plays a key role in early hypertrophic responses in the single kidney state, its impact on KTx outcomes remains uncertain. This report tests the hypothesis that early IGF-1 exposure reduces KTx survival. <h4>Methods</h4> Population datasets compared incident Death Censored Graft Fai...

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Literature Corpus work: 66bc28b9-c49e-5ef0-a8f4-837813d91f5c
DOI: 10.1101/2024.11.27.24318002

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