Back to search

Article

MiR-30c Plays Diagnostic and Prognostic Roles and Mediates Epithelial–mesenchymal Transition (EMT) and Proliferation of Glioma by Affecting Notch1

2021-08-20

Abstract excerpt

miR-30c functions as a tumor suppressor gene in the majority of tumors, including glioma. In our study, we discovered that the expression levels of miR-30c in glioma tissues and plasma prior to operation were lower than that in normal brain tissue following brain injury decompression and plasma in healthy volunteers. The low expression of miR-30c was closely aligned with WHO grade, tumor size, PFS, and OS. Additio...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
66a5c612-81cc-52bf-a314-f45e2ec3ad5f
DOI
10.21203/rs.3.rs-799131/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
MiR-30c Plays Diagnostic and Prognostic Roles and Mediates Epithelial–mesenchymal Transition (EMT) and Proliferation of Glioma by Affecting Notch1DOI 10.21203/rs.3.rs-799131/v1
miR-30 overexpression promotes glioma stem cells by regulating Jak/STAT3 signaling pathwaySemantic proximity
SNHG29 regulates miR-223-3p/CTNND1 axis to promote glioblastoma progression via Wnt/β-catenin signaling pathwaySemantic proximity
Non-coding RNAs as Key Regulators of the Notch Signaling Pathway in Glioblastoma: Diagnostic, Prognostic, and Therapeutic TargetsSemantic proximity
Interferon-γ inducible protein 30 promotes the epithelial-mesenchymal transition-like phenotype and chemoresistance by activating EGFR/AKT/GSK3β/β-catenin pathway in glioma.Semantic proximity
Clinicopathological role of miR-30a-5p in hepatocellular carcinoma tissues and prediction of its function with bioinformatics analysisSemantic proximity
Role of microRNAs in gliomagenesis: targeting miRNAs in glioblastoma multiforme therapySemantic proximity
Long Non-Coding RNA in Glioma: Target miRNA and Signaling PathwaysSemantic proximity
Long Non-Coding RNA LINC00663 Promotes Gliomagenesis and ProgressionSemantic proximity
Role of MicroRNAs in Malignant GliomaSemantic proximity
Up-regulation of miR-663a inhibits the cancer stem cell-like properties of glioma via repressing the KDM2A-mediated TGF-β/SMAD signaling pathwaySemantic proximity
The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG networkSemantic proximity
miRNA Multiplayers in glioma. From bench to bedside.Semantic proximity
Select a neighboring publication to make it the new centre.