Article

Computational modeling of virucidal inhibition mechanism for broad-spectrum antiviral nanoparticles and HPV16 capsid segments

2021-08-22

Abstract excerpt

Solid core nanoparticles coated with sulfonated ligands that mimic heparan sulfate proteoglycans (HSPG) can exhibit virucidal activity against many viruses that utilize HSPG interactions with host cells for the initial stages of the infection. How the interactions of these nanoparticles with large capsid segments of HSPG-interacting viruses lead to their virucidal activity has been unclear. Here, we describe the i...

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Identifiers and source

Literature Corpus work: 6665168c-cd22-5dd7-9c69-17074649ed54
DOI: 10.1101/2021.08.21.457236

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