Article

A Multi-Objective Scoring (MOS) Framework for Detecting Cross-Modal Spatial Similarity: Conceptual and Direct Formulations

2026-04-13

Abstract excerpt

Spatial multi-omics methods allow researchers to study complex biological systems by integrating multiple molecular layers while preserving their spatial organization. However, integrating spatial transcriptomics and mass spectrometry imaging (MSI) remains challenging due to the differences between the two modalities, including sampling geometry, spatial resolution, signal scaling, and measurement principles. For...

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Literature Corpus work: a5085691-fcc4-53cf-b136-9d0d8624e8e0
DOI: 10.64898/2026.04.09.717471

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