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Article

High-dose pyruvate treatment alters skeletal muscle differentiation and expression of inflammation-related genes

2020-09-22

Abstract excerpt

<h4>ABSTRACT</h4> Pyruvic acid therapy is used for various diseases, but the therapeutic effect decreases at high doses. The molecular mechanism of high-dose pyruvate is not well understood. The purpose of this study was to identify the effects of high dose pyruvate addition on skeletal muscle using C2C12. The gene expression profile for the GSE5497 dataset was taken from the Gene Expression Omnibus database. GEO...

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Literature Corpus work
65fdf028-ec98-54de-b996-8693b814943a
DOI
10.1101/2020.09.21.305847
Open publication

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High-dose pyruvate treatment alters skeletal muscle differentiation and expression of inflammation-related genesDOI 10.1101/2020.09.21.305847
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