Article

Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension

2023-01-16

Abstract excerpt

Pulmonary arterial hypertension (PAH) remains an incurable and often fatal disease despite currently available therapies. Multiomics systems biology analysis can shed new light on PAH pathobiology and inform translational research efforts. Using RNA sequencing on the largest PAH lung biobank to date (96 disease and 52 control), we aim to identify gene co-expression network modules associated with PAH and potential...

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Literature Corpus work: 65b97952-a361-5cf1-a32d-fadb44c4c4b8
DOI: 10.1101/2023.01.12.523812

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