Article

Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma

2020-12-11

Abstract excerpt

Recent developments in immuno-oncology demonstrate that not only cancer cells, but also features of the tumor microenvironment guide precision medicine. Still, the relationship between tumor and microenvironment remains poorly understood. To overcome this limitation and identify clinically relevant microenvironmental and cancer features, we applied single-cell RNA sequencing to lung adenocarcinomas. While the high...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 659dd6cc-d850-5577-8aa9-a98fb1247cfb
DOI: 10.1101/2020.12.11.419606

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinomaDOI 10.1101/2020.12.11.419606Read

Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinomaSemantic proximity Read

Characterizing Tumor Microenvironment and Risk Genes in Lung Adenocarcinoma through scRNA-seq and Bulk RNA-seq DataSemantic proximity Read

Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancerSemantic proximity Read

Single-cell RNA sequencing reveals potential therapeutic targets in the tumor microenvironment of lung squamous cell carcinomaSemantic proximity Read

Single-cell RNA sequencing reveals heterogeneous tumor and immune cell populations in early-stage lung adenocarcinomas harboring EGFR mutations.Semantic proximity Read

Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma.Semantic proximity Read

Single-Cell RNA Sequencing in Lung Cancer: Revealing Phenotype Shaping of Stromal Cells in the Microenvironment.Semantic proximity Read

Single-cell transcriptomic profiling reveals the tumor heterogeneity of small-cell lung cancerSemantic proximity Read

A single-cell characterised signature integrating heterogeneity and microenvironment of lung adenocarcinoma for prognostic stratificationSemantic proximity Read

The single-cell transcriptional landscape of lung carcinoid tumorsSemantic proximity Read

Promising immunotherapeutic targets in lung cancer based on single-cell RNA sequencingSemantic proximity Read

Spatiotemporal Profiling Unveiling the Cellular Organization Patterns and Local Protumoral Immune Microenvironment Remodeling in Early Lung Adenocarcinoma ProgressionSemantic proximity Read