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The Role of PIWIL4, an Argonaute Family Protein, in Breast Cancer

8 Mar 2016

Abstract excerpt

P-element-induced wimpy testis (PIWI) proteins bind to PIWI-interacting RNAs and play key roles in the biogenesis and functions of PIWI-interacting RNAs. It has been reported that PIWI proteins are essential for stem cell self-renewal and germline development in diverse organisms and that they are ectopically expressed in multiple forms of cancer. However, the role of PIWI in cancer remains elusive. Here we...

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PMID: 26957540
DOI: 10.1074/jbc.m116.723239

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