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Digital Spatial Profiling of Intraductal Papillary Mucinous Neoplasms: Towards a Molecular Framework for Risk Stratification

2022-09-12

Abstract excerpt

The histopathologic heterogeneity of intraductal papillary mucinous neoplasms (IPMN) complicates the prediction of pancreatic ductal adenocarcinoma (PDAC) risk. Intratumoral regions of pancreaticobiliary (PB), intestinal (INT), and gastric foveolar (GF) epithelium may occur with either low-grade dysplasia (LGD) or high-grade dysplasia (HGD). We used digital spatial RNA profiling of dysplastic epithelium (83 region...

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Literature Corpus work
652e1a32-c75a-59be-8ca4-bff1dffedbe3
DOI
10.1101/2022.09.08.507112
Open publication

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Digital Spatial Profiling of Intraductal Papillary Mucinous Neoplasms: Towards a Molecular Framework for Risk StratificationDOI 10.1101/2022.09.08.507112
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