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Investigating the contribution of circulating inflammatory cytokines on the link between obesity and COVID-19

2025-02-10

Abstract excerpt

<h4>Background</h4> Coronavirus disease 2019 (COVID-19), is more severe in individuals with obesity. Furthermore, a cytokine storm was observed in many critically ill patients with COVID-19. Since adipose tissue secretes cytokines, we investigated whether cytokines mediate the effect of obesity on COVID-19 severity. <h4>Methods</h4> Using two-sample Mendelian randomization analyses we assessed the causal effect of...

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Literature Corpus work
64eacc7a-9bb9-5f87-b7e4-a57e33e8f164
DOI
10.1101/2025.02.07.25321874
Open publication

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