Article

Unsupervised explainable AI reveals similar oligonucleotide-usage zones matching the highest-resolution human chromosome bands

2026-03-11

Abstract excerpt

<h4>ABSTRACT</h4> Unsupervised and explainable AI can uncover genomic features that extend beyond human expectations. Oligonucleotides such as penta- and hexanucleotides often function as core binding motifs for regulatory proteins, and their usage provides a powerful tool in functional genomics. We applied an unsupervised, explainable AI approach to odds ratio (observed/expected) profiles of all 1-Mb euchromatic...

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Literature Corpus work: 64e6540e-e83f-5714-86f7-54b19524fefe
DOI: 10.64898/2026.03.09.710446

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