Article

Freezing responses during prolonged threat memory retrieval reflect trait-like anxiety endophenotypes in female and male inbred mice

2023-11-22

Abstract excerpt

Trait anxiety is a major risk factor for stress-induced and anxiety disorders in humans. However, animal models accounting for the inter-individual variability in stress vulnerability are largely lacking. Moreover, the pervasive bias of using mostly male animals in preclinical studies poorly reflects the increased prevalence of psychiatric disorders in women. Using the threat imminence continuum theory, we designe...

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Literature Corpus work: 64d8cb81-6161-52ab-a5bd-a2df6bc63fd9
DOI: 10.1101/2023.11.22.568236

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Freezing responses during prolonged threat memory retrieval reflect trait-like anxiety endophenotypes in female and male inbred miceDOI 10.1101/2023.11.22.568236Read

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