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Article

FGFR3 mutation characterization identifies prognostic and immune-related gene signatures in bladder cancer.

Computers in biology and medicine - 1 Aug 2023

Xu Pei-Hang, Chen Siyuan, Wang Yanhao, Jin Shengming, Wang Jun, Ye Dingwei, Zhu Xiaodong, Shen Yijun

Abstract excerpt

BACKGROUND: Immunotherapy and FGFR3-targeted therapy play an important role in the management of locally advanced and metastatic bladder cancer (BLCA). Previous studies indicated that FGFR3 mutation (mFGFR3) may be involved in the alterations of immune infiltration, which may affect the priority or combination of these two treatment regimes. However, the specific impact of mFGFR3 on the immunity and how FGFR3...

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Identifiers

PMID: 37301098
DOI: 10.1016/j.compbiomed.2023.106976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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