Article

Developmentally inspired bioprinting of nascent multicellular human heart tissue through <i>in situ</i> differentiation and morphogenesis of iPSCs

2026-01-14

Abstract excerpt

Traditional heart tissue bioprinting typically relies on using human induced pluripotent stem cell (iPSC)-derived cardiomyocytes that are pre-differentiated in 2D culture. This approach differs fundamentally from embryonic heart development, where mesodermal progenitors differentiate into cardiomyocytes within 3D, matrix-rich, and shape-morphing microenvironments. Here, we introduce a novel developmentally inspire...

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Literature Corpus work: 634b0578-2f06-57e5-8fb8-a0c08f2ae7e2
DOI: 10.64898/2026.01.13.699298

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