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ANALYSIS OF THE REPLICATION KINETICS OF THE CHIMERIVAX™-DEN 1, 2, 3, 4 TETRAVALENT VIRUS MIXTURE IN AEDES AEGYPTI BY REAL-TIME REVERSE TRANSCRIPTASE–POLYMERASE CHAIN REACTION

2004-01-01

Abstract excerpt

The vector competence of mosquitoes for chimeric viruses being developed as vaccines to protect against dengue (DEN) virus infection were evaluated in a cooperative agreement with Acambis, Inc. Chimeric viruses have been constructed that contain the premembrane (prM) and envelope (E) genes of each of the wild-type (wt) DEN virus serotypes, DEN-1, DEN-2, DEN-3, and DEN-4, in the yellow fever (YF) vaccine virus (str...

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Literature Corpus work
6349bf9c-0427-5921-8c3a-9ecb10d6da62
DOI
10.4269/ajtmh.2004.70.89
Open publication

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ANALYSIS OF THE REPLICATION KINETICS OF THE CHIMERIVAX™-DEN 1, 2, 3, 4 TETRAVALENT VIRUS MIXTURE IN AEDES AEGYPTI BY REAL-TIME REVERSE TRANSCRIPTASE–POLYMERASE CHAIN REACTIONDOI 10.4269/ajtmh.2004.70.89
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