Replication Kinetics of a Candidate Live-Attenuated Vaccine for Cache Valley Virus in Aedes albopictus

doi:10.1089/vbz.2022.0053

Article

Replication Kinetics of a Candidate Live-Attenuated Vaccine for Cache Valley Virus in Aedes albopictus

1 Nov 2022

Abstract excerpt

Background: The emergence or re-emergence of several orthobunyaviruses (order: Bunyavirales ; family: Peribunyaviridae ), including Cache Valley virus (CVV) and Oropouche virus, warrants the development and evaluation of candidate live-attenuated vaccines (LAVs). Ideally, these vaccines would elicit long-lasting immunity with one single immunization. Materials and Methods: Since the deletion of two virulence...

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