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Development of a Live Attenuated Dengue Virus Vaccine Using Reverse Genetics

1 Mar 2006

Abstract excerpt

There are four serotypes of dengue (DEN1-DEN4) virus that are endemic in most areas of Southeast Asia, Central and South America, and other subtropical regions. The number of cases of severe disease associated with DEN virus infection is growing because of the continued spread of the mosquito vector, Aedes aegypti, which transmits the virus to humans. Infection with DEN virus can result in an asymptomatic...

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Identifiers

PMID: 16553547
DOI: 10.1089/vim.2006.19.10

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