Article

In silico dynamics of COVID-19 phenotypes for optimizing clinical management

2020-09-03

Abstract excerpt

Understanding the underlying mechanisms of COVID-19 progression and the impact of various pharmaceutical interventions is crucial for the clinical management of the disease. We developed a comprehensive mathematical framework based on the known mechanisms of the SARS-CoV-2 virus infection, incorporating the renin-angiotensin system and ACE2, which the virus exploits for cellular entry, key elements of the innate a...

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Literature Corpus work: 631afeb8-4246-5d59-9036-977aa7a17898
DOI: 10.21203/rs.3.rs-71086/v1

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