Article

Decoding <i>Helicobacter pylori</i> Resistance: Machine Learning–Enhanced Prediction of Antibiotic Susceptibility using Whole-Genome Sequencing

2025-08-07

Abstract excerpt

<h4>Background</h4> Helicobacter pylori is a significant risk factor for gastric cancer, peptic ulcers, and MALT lymphoma. Rising antibiotic resistance rates complicate treatment strategies. While nucleotide sequence based assays are reliable in predicting clarithromycin and levofloxacin resistance, predicting metronidazole resistance is more challenging due to diverse metabolic pathways contributing to resistanc...

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Literature Corpus work: 6311a5ad-5cb1-5b78-a15c-84bc2a9484bc
DOI: 10.1101/2025.08.07.669068

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