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Article

Genomic determinants of antibiotic resistance for Helicobacter pylori treatment: a retrospective phenotypic and genotypic observational study.

The Lancet. Microbe - 1 Jan 2026

Martínez-Martínez Francisco José, Chiner-Oms Álvaro, Furió Victoria, Yamaoka Yoshio, Dekker John P, Mégraud Francis, Bénéjat Lucie, Ducournau Astrid, Giese Alban, Jehanne Quentin, Jauvain Marine, Camargo M Constanza, Comas Iñaki, Lehours Philippe

Abstract excerpt

BACKGROUND: Rising antimicrobial resistance of Helicobacter pylori is a public health challenge. Genomic-based susceptibility testing allows for the identification of resistance-associated mutations, complementing conventional diagnostics and advancing towards pathogen-based personalised therapies. Our study aimed to identify genes and mutations involved in antimicrobial resistance in H pylori and evaluate the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 41453373
DOI: 10.1016/j.lanmic.2025.101217
PMCID: PMC12961094

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