Article

Cosmopolitan inversions have a major impact on trait variation and the power of different GWAS approaches to identify associations

2025-09-20

Abstract excerpt

The ability of genomic inversions to reduce recombination and generate linkage can have a major impact on genetically based phenotypic variation in populations. However, the increase in linkage associated with inversions can create hurdles for identifying associations between loci within inversions and the traits they impact. As a consequence, the role of inversions in mediating genetic variation in complex traits...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 62861039-731f-5709-a44a-debe43379fa5
DOI: 10.1101/2025.09.17.676858

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Cosmopolitan inversions have a major impact on trait variation and the power of different GWAS approaches to identify associationsDOI 10.1101/2025.09.17.676858Read

The Influence of Chromosomal Inversions on Genetic Variation and Clinal Patterns in Genomic Data of Drosophila melanogaster.Semantic proximity Read

Towards a complete characterization of common human polymorphic inversions and their functional effectsSemantic proximity Read

Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster.Semantic proximity Read

Large inversion polymorphisms are widespread in North American songbirdsSemantic proximity Read

Linked genetic variation and not genome structure causes widespread differential expression associated with chromosomal inversions.Semantic proximity Read

Mapping regions within cosmopolitan inversion In(3R)Payne associated with natural variation in body size in Drosophila melanogaster.Semantic proximity Read

A survey of current methods to detect and genotype inversions.Semantic proximity Read

The effect of genomic inversions on estimation of population genetic parameters from SNP data.Semantic proximity Read

Identification of polymorphic inversions from genotypes.Semantic proximity Read

Linkage Disequilibrium and Inversion-Typing of the Drosophila melanogaster Genome Reference Panel.Semantic proximity Read

Functional and evolutionary impact of polymorphic inversions in the human genomeSemantic proximity Read

Determining the impact of uncharacterized inversions in the human genome by droplet digital PCRSemantic proximity Read