Article
Inference of chromosomal inversion dynamics from Pool-Seq data in natural and laboratory populations of Drosophila melanogaster.
Molecular ecology - 1 Apr 2014
Kapun Martin, van Schalkwyk Hester, McAllister Bryant, Flatt Thomas, Schlötterer Christian
Abstract excerpt
Sequencing of pools of individuals (Pool-Seq) represents a reliable and cost-effective approach for estimating genome-wide SNP and transposable element insertion frequencies. However, Pool-Seq does not provide direct information on haplotypes so that, for example, obtaining inversion frequencies has not been possible until now. Here, we have developed a new set of diagnostic marker SNPs for seven cosmopolitan...
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