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Mutational analysis of LtgC, a lytic transglycosylase required for cell separation in <i>Neisseria gonorrhoeae</i>

2023-06-20

Abstract excerpt

Lytic transglycosylases function to degrade peptidoglycan strands that comprise the bacterial cell wall. Degradation of peptidoglycan at the septum following cell division is necessary for cell separation, and a deletion of ltgC in Neisseria gonorrhoeae results in growth in clusters of around 6-20 cells rather than as normal diplococci or monococci. N. gonorrhoeae LtgC is a homolog of Escherichia coli MltA, an...

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Literature Corpus work
626a8565-1d0b-5eef-a0e2-1ba67666f146
DOI
10.1101/2023.06.20.545760
Open publication

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Mutational analysis of LtgC, a lytic transglycosylase required for cell separation in <i>Neisseria gonorrhoeae</i>DOI 10.1101/2023.06.20.545760
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