Article

In Vivo Spatial Transcriptomics for Bleeding-free Profiling Human Internal Organs

2026-07-09

Abstract excerpt

Despite the significant technical advancement in spatial transcriptomics, its clinical usage is largely untapped. Here, we develop an integrated system, ENDO-Genome, for minimally invasive in-body transcript sampling to facilitate live spatial transcriptomic analysis of human internal organs. This is achieved by integrating a nanoarrayed biochip with existing endoscope to perform pressure-sensor-calibrated “Touch...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 62567136-07ef-5a06-8ee3-10fe0983fdc2
DOI: 10.64898/2026.07.06.26357355

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

In Vivo Spatial Transcriptomics for Bleeding-free Profiling Human Internal OrgansDOI 10.64898/2026.07.06.26357355Read

Sub-cellular Imaging of the Entire Protein-Coding Human Transcriptome (18933-plex) on FFPE Tissue Using Spatial Molecular ImagingSemantic proximity Read

High Resolution Single Cell Maps Reveals Distinct Cell Organization and Function Across Different Regions of the Human IntestineSemantic proximity Read

Single-cell transcriptomic mapping of intestinal epithelium that undergoes 3D morphogenesis and mechanodynamic stimulation in a gut-on-a-chipSemantic proximity Read

Single-cell transcriptomics elucidates <i>in vitro</i> reprogramming of human intestinal epithelium cultured in a physiodynamic gut-on-a-chipSemantic proximity Read

RNA liquid biopsy via nanopore sequencing for novel biomarker discovery and cancer early detectionSemantic proximity Read

Organization of the human intestine at single-cell resolutionSemantic proximity Read

A Practical Guide to Spatial Transcriptomics: Lessons from over 1000 SamplesSemantic proximity Read

Subcellular Imaging of the Entire Protein Coding Human Transcriptome on FFPE Tissue Using Spatial Molecular ImagingSemantic proximity Read

Single-cell spatial transcriptomics of fixed, paraffin-embedded biopsies reveals colitis-associated cell networksSemantic proximity Read

Transcriptome comparisons of in vitro intestinal epithelia grown under static and microfluidic gut-on-chip conditions with in vivo human epitheliaSemantic proximity Read

Single-cell transcriptomics of rectal organoids from individuals with perianal fistulizing Crohn’s disease reveals patient-specific signaturesSemantic proximity Read

The spatial transcriptomic landscape of the healing intestine following damageSemantic proximity Read