Article

Identification of transcriptional regulators using a combined disease module identification and prize-collecting Steiner tree approach

2024-02-05

Abstract excerpt

Transcription factors play important roles in maintaining normal biological function, and their dys-regulation can lead to the development of diseases. Identifying candidate transcription factors involved in disease pathogenesis is thus an important task for deriving mechanistic insights from gene expression data. We developed Transcriptional Regulator Identification using Prize-collecting Steiner trees (TRIPS), a...

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Literature Corpus work: 623f2b60-542e-54e6-a256-1c2d94ee3687
DOI: 10.1101/2024.02.05.577574

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