Back to search

Article

Long non-coding RNA PGM5-AS1 modulates epithelial-mesenchymal transition and invasion and metastasis of osteosarcoma cells by impairing miR-140-5p-mediated FBN1 inhibition

2019-12-31

Abstract excerpt

<title>Abstract</title> <p>Background Osteosarcoma represents a uncommon tumor occurring in bone possessing elevated rate of incidence and reduced rate of healing. Hence, developing effective therapeutic modalities to treat osteosarcoma is essential. Various long non-coding RNAs (lncRNAs) are engaged in prognostic and diagnostic processes of diseases. Thus, we identified the molecular mechanism of lncRNA PGM5-AS1...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
622914cb-ad7f-5ebe-8ab7-83bd94429496
DOI
10.21203/rs.2.19800/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Long non-coding RNA PGM5-AS1 modulates epithelial-mesenchymal transition and invasion and metastasis of osteosarcoma cells by impairing miR-140-5p-mediated FBN1 inhibitionDOI 10.21203/rs.2.19800/v1
The role of long non-coding RNA FGD5-AS1 in cancerSemantic proximity
LncRNA GAS5 suppresses the proliferation and invasion of osteosarcoma cells via the miR-23a-3p/PTEN/PI3K/AKT pathwaySemantic proximity
MicroRNA-744-5p Suppresses Tumorigenesis and Metastasis of Osteosarcoma Through the MAPK/ERK Signaling Pathway by Targeting TGFB1Semantic proximity
Long non‑coding RNA NR2F1‑AS1 facilitates the osteosarcoma cell malignant phenotype via the miR‑485‑5p/miR‑218‑5p/BIRC5 axis.Semantic proximity
Comprehensive analysis of potential cellular communication networks in advanced osteosarcoma using single-cell RNA sequencing dataSemantic proximity
Long non-coding RNAs in osteosarcomaSemantic proximity
COL5A2 Inhibits the TGF-β and Wnt/β-Catenin Signaling Pathways to Inhibit the Invasion and Metastasis of OsteosarcomaSemantic proximity
LncRNA MAFG-AS1 promotes the malignant phenotype of ovarian cancer by upregulating NFKB1-dependent IGF1.Semantic proximity
The multiple function of long noncoding RNAs in osteosarcoma progression, drug resistance and prognosisSemantic proximity
Comprehensive analysis of hsa-miR-654-5p’s tumor-suppressing functionsSemantic proximity
ANGPTL4 Negatively Regulate the Progression of Osteosarcoma by Remodeling Branched-Chain Amino Acid MetabolismSemantic proximity
Silencing of SNHG6 induced cell autophagy by targeting miR-26a-5p/ULK1 signaling pathway in human osteosarcomaSemantic proximity
Select a neighboring publication to make it the new centre.