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Article

LncRNA MAFG-AS1 promotes the malignant phenotype of ovarian cancer by upregulating NFKB1-dependent IGF1.

Cancer gene therapy - 1 Mar 2022

Bai Yang, Ren Chenchen, Wang Baojin, Xue Jingge, Li Feiyan, Liu Jiaxi, Yang Li

Abstract excerpt

Long non-coding RNAs (lncRNAs) were recently recognized to vitally function in a variety of cancer cellular events, including epithelial-mesenchymal transition (EMT), invasion, and migration, particularly in ovarian cancer (OC). Herein, we sought to investigate the potential role of MAFG-AS1 in the malignant behaviors of OC cells. The binding affinity between MAFG-AS1, miR-339-5p, NFKB1 or IGF1 was characterized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34035482
DOI: 10.1038/s41417-021-00306-8

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