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Genetic variants of calcium and vitamin D metabolism in kidney stone disease

2019-01-14

Abstract excerpt

Kidney stone disease (nephrolithiasis) is a major clinical and economic health burden 1,2 with a heritability of ~45-60% 3 . To identify genetic variants associated with nephrolithiasis we performed genome-wide association studies (GWAS) and meta-analysis in British and Japanese populations, including 12,123 nephrolithiasis cases and 416,928 controls. Twenty loci associated with nephrolithiasis were identified,...

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Literature Corpus work
621f3a87-d0c0-550e-be1b-dfec72975fb4
DOI
10.1101/515882
Open publication

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Genetic variants of calcium and vitamin D metabolism in kidney stone diseaseDOI 10.1101/515882
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