Article

Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mapping

2024-07-28

Abstract excerpt

The ability to spatially map multiple layers of the omics information over different time points allows for exploring the mechanisms driving brain development, differentiation, arealization, and alterations in disease. Herein we developed and applied spatial tri-omic sequencing technologies, DBiT ARP-seq (spatial ATAC–RNA–Protein-seq) and DBiT CTRP-seq (spatial CUT&Tag– RNA–Protein-seq) together with multiplexed i...

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Literature Corpus work: 61ddedbd-fcc3-5d1f-b372-4952ce2722de
DOI: 10.1101/2024.07.28.605493

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