Article

Tracking breast cancer progression using Methylscape

2025-07-15

Abstract excerpt

Cancer progression is intricately driven by epigenetic reprogramming, where aberrant DNA methylation patterns reshape gene regulation and cellular phenotypes. These alterations include promoter hypermethylation of tumour suppressor genes and global hypomethylation, collectively fuelling oncogenesis and disease advancement. We previously introduced the Methylscape —a distinct cancer-specific DNA methylation landsc...

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Literature Corpus work: 61c0449b-f24d-5767-b9be-2c6f6c0223c5
DOI: 10.1101/2025.07.09.664004

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