Article

Switch-like Gene Expression Modulates Disease Susceptibility

2024-08-26

Abstract excerpt

A fundamental challenge in biomedicine is understanding the mechanisms predisposing individuals to disease. While previous research has suggested that switch-like gene expression is crucial in driving biological variation and disease susceptibility, a systematic analysis across multiple tissues is still lacking. By analyzing transcriptomes from 943 individuals across 27 tissues, we identified 1,013 switch-like gen...

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Literature Corpus work: 60f933b5-d5a1-5312-9b88-159295b80995
DOI: 10.1101/2024.08.24.609537

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