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Article

Switch-like genes populate cell communication pathways and are enriched for extracellular proteins.

BMC genomics - 4 Jan 2008

Ertel Adam, Tozeren Aydin

Abstract excerpt

BACKGROUND: Recent studies have placed gene expression in the context of distribution profiles including housekeeping, graded, and bimodal (switch-like). Single-gene studies have shown bimodal expression results from healthy cell signaling and complex diseases such as cancer, however developing a comprehensive list of human bimodal genes has remained a major challenge due to inherent noise in human microarray...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18177501
DOI: 10.1186/1471-2164-9-3
PMCID: PMC2257939

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