Article

Multiparametric Assessment of TNNI3 Variant Phenotypes in Human iPSC-Cardiomyocytes Correlates with Disease Severity in Patients

2025-12-16

Abstract excerpt

<h4>Background</h4> The routine genetic testing of cardiomyopathy patients has significantly accelerated the identification of causative cardiomyopathy variants. However, translating these genetic insights into effective patient management poses significant challenges, since the impact of gene variants on physiological function and clinical outcomes is not yet fully understood. Therefore, there is an urgent need...

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Literature Corpus work: 609cba34-45ec-588f-9373-f66156dc7735
DOI: 10.64898/2025.12.13.691658

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