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Therapeutic targeting of oligodendrocytes in an agent-based model of multiple sclerosis

2025-06-27

Abstract excerpt

Multiple sclerosis (MS) is a neurodegenerative disease in which misdirected, persistent activity of the immune system degrades the protective myelin sheaths of nerve axons. Historically, treatment of MS has relied on disease-modifying therapies that involve immunosuppression, such as targeting of the blood-brain barrier (BBB) to restrict lymphocyte movement. New therapeutic ideas in the development pipeline are in...

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Literature Corpus work
601b5443-9d9c-5030-b984-c1ac289cce39
DOI
10.1101/2025.06.26.661705
Open publication

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Therapeutic targeting of oligodendrocytes in an agent-based model of multiple sclerosisDOI 10.1101/2025.06.26.661705
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