Article

Genetic characteristics of platinum-sensitive ovarian clear cell carcinoma

2022-06-24

Abstract excerpt

<h4>Background: </h4> Most ovarian clear cell carcinomas (OCCCs) are resistant to platinum-based chemotherapy, while a small subset shows a positive response. The aim of this study was to clarify the clinical, pathological, and genetic characteristics of platinum-sensitive OCCCs. <h4>Methods: </h4> The study included 53 patients with stage III–IV OCCC who had residual tumors after primary surgery and received plat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5fc178f8-081a-5601-9a62-118df44a80ee
DOI: 10.21203/rs.3.rs-1766534/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic characteristics of platinum-sensitive ovarian clear cell carcinomaDOI 10.21203/rs.3.rs-1766534/v1Read

Genetic characteristics of platinum-sensitive ovarian clear cell carcinoma.Semantic proximity Read

Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer.Semantic proximity Read

Mutational profiles of ovarian cancer in Chinese patients reveal potential therapeutic targets and prognostic markersSemantic proximity Read

Tailoring Ovarian Cancer Treatment: Implications of BRCA1/2 MutationsSemantic proximity Read

Molecular profiling reveals novel therapeutic targets and clonal evolution in ovarian clear cell carcinoma.Semantic proximity Read

Clinicopathological and Prognostic Values of Telomerase Reverse Transcriptase (TERT) Promoter Mutations in Ovarian Clear Cell Carcinoma for Predicting Tumor Recurrence, Platinum Resistance and Survival.Semantic proximity Read

Reversing Platinum Resistance in High-Grade Serous Ovarian Carcinoma: Targeting BRCA and the Homologous Recombination SystemSemantic proximity Read

The clinical features associated with mutated BRCA1 and 2 genes in ovarian cancer patients.Semantic proximity Read

Critical molecular abnormalities in high-grade serous carcinoma of the ovary.Semantic proximity Read

Ovarian Clear Cell Carcinoma: Genomic Characterization, Pathogenesis and Targeted TherapySemantic proximity Read

Association Between TP53 Mutations and Platinum Resistance in a Cohort of High-Grade Serous Ovarian Cancer Patients: Novel Implications for Personalized TherapeuticsSemantic proximity Read

Review the progression of ovarian clear cell carcinoma from the perspective of genomics and epigenomicsSemantic proximity Read