Article

Cisplatin resistant lung adenocarcinoma cells exhibit increased proangiogenic capacity in a microphysiological model of tumor neovascularization

2025-08-22

Abstract excerpt

Carcinomas commonly recur and progress rapidly after a period of remission following platinum-based therapy. This clinical scenario suggests that surviving drug-resistant tumor cells are dormant or slow cycling before re-entering a rapid growth phase. Remodeling of the recurrent tumor microenvironment (TME) contributes to high rates of metastasis, but little is known about differences in TME remodeling before ther...

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Literature Corpus work: 5faa6b1c-5181-506e-8d7f-d00f21b663e1
DOI: 10.1101/2025.08.18.670623

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